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295,296 Restoring MT1 expression in cells lacking MT results in the recovery of NF-B p65 subunit levels, along with a subsequent increase in NF-B activity related to cellular signaling, and improved protection against apoptosis

Mandlekar and Kong, 2001), was also significantly attenuated by GSTP1 (Supplementary Figure S4), which cannot be explained by GSTP1-mediated inactivation of reactive metabolites in the absence of bioactivation of tamoxifen in HepG2 cells

PMID: 93 ShimizuK.OguraH.OdaJ

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