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After coronary artery ligation in mice, intraperitoneal T4 treatment upregulated cardiac ILK and Akt activity, enhanced early myocyte survival, and improved cardiac function establishing the mechanistic basis for the cardiac and broader tissue-repair claims associated with thymosin beta-4 and its 1723 fragment TB-500

Elje E, Mariussen E, Moriones OH, Basts NG, Puntes V, Kohl Y, et al

Perilesional astrocytic border (again contrary to a widespread beliefs) is permissive for axonal outgrowth and tissue recovery