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While the pathological and clinical presentations of neurodegenerative diseases vary, they share common features including specific pathological alterations within distinct brain regions and the degeneration of various neuronal subtypes

However, when stem cells are exposed to higher copper levels, they progress into differentiated cells

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Together, these findings suggest that both CoQ biosynthesis and intracellular transport represent potential therapeutic nodes for modulating ferroptosis, particularly in disease contexts such as therapy-resistant cancers