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Tolerability and Safety Common side effects of popular GLP-1 medications are usually transient and can include: Nausea Diarrhea Constipation Early satiety Gastrointestinal upset during dose escalation Hydration, changes to meal size, and slower titration may help with these effects

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Vitamin B12 injections are generally safe, but some individuals may experience side effects, including: Pain or redness at the injection site Mild diarrhea Itching Nausea or vomiting Dizziness or headaches Hot flashes In rare cases, more serious reactions, such as allergic responses (rash, swelling, trouble breathing), can occur

Tielsch et al., 1995

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