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As always, consult your healthcare provider if you're pregnant, breastfeeding, or have any underlying health conditions.

The oncogene K-Ras activates Nrf2 transcription through the Mek-Erk-Jun signaling pathway and reduces the ROS levels in primary fibroblasts

Diosgenin protects retinal pigment epithelial cells from inflammatory damage and oxidative stress induced by high glucose by activating AMPK/Nrf2/HO-1 pathway

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Parkin-mediated polyubiquitination then facilitates the interaction with autophagy receptors, ultimately leading to autophagosome formation and lysosomal degradation of dysfunctional mitochondria