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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Ishikawa S, Shimano M, Watarai M, Koyasu M, Uchikawa T, Ishii H, et al

This widespread vascular inflammation is intimately and mechanistically connected to dysautonomia and Postural Orthostatic Tachycardia Syndrome (POTS)

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Furthermore, BCAAs act as a major stimulator of mTORC1 signaling (130), suggesting potential interactions between these amino acids and drugs used to inhibit mTOR

PMID: 15100091 Yoshida T, Delafontaine P