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Diabetes Obes Metab 2020;22:126377.PubMedPMC 25

It is dependent on stimulus-secretion coupling, whereby glucose catabolism within pancreatic -cells generates the primary signal for secretion

Proteins containing Cys are prone to multiple posttranslational modifications (thiol-based oxidative PTMs) such as glutathionylation or S -nitrosation, which can affect the metabolism of various molecules such as glutathione or nicotinamide adenine dinucleotide phosphate (NADPH) (Corpas et al

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