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Whereas, the C-terminus undergoes amidation (conversion of the carboxyl group (-COOH) to an amide group (-NH2)

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The authors also acknowledge Heather Edens, PhD, from UCB, Smyrna, Georgia, USA, for publication coordination and Aditi Mehta, MSc, Barney Johnson, BA, and Sona Popat, BA, from Costello Medical, London, UK, for medical writing and editorial assistance based on the authors input and direction

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These findings indicate that compared to other administration routes of vitamin B12, acupoint injection improves neurological function in patients with DN without increasing adverse events and economic burden, suggesting that it may be the optimal administration route for vitamin B12