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doi: 10.1080/15592324.2018.1460048 57 El-SappahA

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Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M: Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

Mice with the NLGN3-R451C mutation exhibit social deficits and behavioral problems, with increased excitatory synaptic transmission in the CA1 region of the hippocampus and enhanced inhibitory synaptic transmission in the 2/3 layers of the somatosensory cortex (86).Enhanced inhibitory synaptic transmission in Purkinje cells is manifested as an increase in the amplitude of mIPSCs, with no significant change in frequency (87)