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Many begin weekly for 46 weeks, then switch to every 24 weeks for maintenance

dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae

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Among the upregulated genes are those encoding DNA repair enzymes (BRCA1, ATM), extracellular matrix proteins (COL1A1, COL3A1, ELN) and antioxidant enzymes (SOD1, SOD2, GPX)

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