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In pregnancies affected by T21, the concentration of advanced glycation end products (AGE) was found to be reduced in both plasma and amniotic fluid samples compared to euploid pregnancies

A Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial for Efficacy of Acetyl-L-carnitine in Patients with Dementia Associated with Cerebrovascular Disease

Others may need diagnostic evaluation before any therapy is considered

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Safety and Tolerability: Gastrointestinal adverse effects, including nausea and vomiting, were commonly reported