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J Korean Med Sci 18: 637640

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Beyond mediating outer mitochondrial membrane fusion, Mfn1/2 participates in mitophagy regulation, mitochondrial cristae remodeling, and facilitates stress-associated unfolded protein response (UPR) (Tokuyama and Yanagi, 2023)

Tesofensine , which affects multiple neurotransmitter systems involved in appetite and metabolism

Quick Answer: Tirzepatide and sermorelin can be used together without known direct contraindications, but this combination lacks clinical trial evidence and requires careful medical supervision