Although liraglutide is the most studied GLP-1 agonist in psychiatric patients and is available in a generic form, it requires daily dosing and is less effective than the branded, once-weekly GLP-1 agonists semaglutide and tirzepatide.
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Together, they contribute to improved metabolic efficiency, reduced fatigue, and support of normal muscle, immune, and reproductive function , particularly in individuals with increased nutritional demands
Brown Norway rats that did not undergo any treatment (PQ or eye drops) were also included as a healthy untreated control group
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