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Brzoska T, Luger TA, Maaser C, Abels C, Bohm M

Our objective was to conduct a literature search to identify all academic reports of GSH use for skin lightening and all clinical trials of GSH use for all indications in medicine

Constitutive activation of NRF2, mainly via loss-of-function mutations in the CUL3-adapter KEAP1 or gain-of-function mutations in NFE2L2 , is thought to provide a fitness advantage to tumor cells in confronting metabolic/oxidative stress resulting from dysregulated growth (DeNicola et al, 2011

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