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Pehlivan FE

doi: 10.1016/j.tips.2022.03.014 57 MarrellaAVaraniGAielloMVaccariIVitaleCMojzisekMet al

Conversion of calcidiol to its biologically active form, calcitriol, occurs through the activity of a specific 25-hydroxyvitamin D 3 1--hydroxylase (commonly just called 1--hydroxylase) present in the inner mitochondrial membrane of cells of the proximal convoluted tubules of the kidneys, and in several extrarenal sites such as in keratinocytes, macrophages, and placenta

The 4-Hydroxynonenal mediated oxidative damage of blood proteins and lipids involves secondary lipid peroxidation reactions

NAC has been shown to eliminate ROS and suppress TGF-1induced profibrotic responses in lung fibroblasts [19, 151, 152]

Mycopathologia 152:3540