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Apigenin has neuroprotective effects in a mouse model of AD (APP/PS1 double transgenic mice), where it improves memory and learning deficits, and reduces fibrillar amyloid deposits by restoring activity of the ERK/CREB/BDNF pathway [111]

2 REIMAGINE 3 was a 40-week phase 3 trial evaluating the safety and efficacy of CagriSema 2.4 mg/2.4 mg and 1 mg/1 mg once weekly versus dose-matched placebo in 274 adults with T2D as add-on to once-daily basal insulin with or without metformin

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SIDE EFFECTS GHK-Cu is characterized by a high safety profile and is generally well-tolerated

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