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Weeks 1 to 4 (introductory phase) use a 1 to 2 percent concentration once daily in the evening, which lets the skin acclimate while the physician assesses tolerance

Nausea, vomiting, diarrhea, and constipation are common, especially in the early weeks of treatment

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Extracellular vesicles from Lacticaseibacillus paracasei reduce neuroinflammation in hippocampus and restore some cognitive functions in hyperammonemic rats

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