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While inhaled corticosteroids like budesonide can have minimal systemic absorption, the risk of decreased bone mineral density is primarily associated with long-term, high-dose use rather than short-term or intermittent rescue use of Airsupra

Human serum was acquired from Merck Millipore

In some embodiments, the formulation or composition comprises between about 0.01% to about 9% by weight of the viscosity modulating agent

In addition, ferroptosis associated with mitochondrial morphological changes, such as smaller size and increased membrane density, was implicated in PET NPs-induced lung injury

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