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Scand J Gastroenterol 49(2):222237
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Overall, these three OSMs play a crucial role in the pathogenesis and progression of IBD and have been suggested to serve as potential diagnostic, differential, progression, and prognostic markers in the disease
The melanocortin system, the common root of the two peptides It's impossible to compare Melanotan 2 and PT-141 without first setting the scene
In particular, the differences between FoB and MZB in recirculation properties 49 , the exposure to oxygen levels, and in degree of activation upon stimulation 48 , have raised interest in their metabolic dependencies
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