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Atalay M, Laaksonen DE: Diabetes, oxidative stress and physical exercise

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A reduction in GSH levels was also found, which could be both, cause or consequence of the decrease in GPx and GR activities

Glutathione, when used as a supplement for skin whitening, has been shown to be safe and effective in numerous clinical studies, and according to a double-blind placebo-controlled clinical trial by National Institute of Health [1], Glutathione treatment has been proven to significantly lower the skin melanin index of study participants after a few weeks of use