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When speaking to your GP, it may be helpful to: Be honest about your weight history and any previous attempts at lifestyle modification or pharmacological treatment

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Excessive weight loss beyond normal BMI risks adverse effects like impaired immunity, hormonal dysregulation, and reduced bone density are key considerations when overcoming plateaus for sustained reduction [44]

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Given the high biological potency of retatrutide, small quality variations can have substantial effects, making reliable testing a key step in reducing uncertainty