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Once the oxidative threat has passed and the cellular redox balance is restored, specialized enzymes such as glutaredoxin (Grx) or thioredoxin (Trx) carefully remove the glutathione cap, returning the protein to its normal, functional state

Muneoka K, Kuwagata M, Ogawa T, Shioda S (2015) Mother/offspring co-administration of the traditional herbal remedy yokukansan during the nursing period influences grooming and cerebellar serotonin levels in a rat model of neurodevelopmental disorders

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The expression of target genes was analysed via quantitative real-time PCR with a QuantaStudio 5 qPCR machine (Applied Biosystems, Thermo Fisher Scientific)

Balkan Med J 33:188192