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1 Introduction Parkinsons disease (PD) is the most common movement disorder and the second most prevalent neurodegenerative disease ( Given the incomplete understanding of PDs underlying pathological mechanisms, current therapeutic strategies primarily offer symptomatic relief rather than halting disease progression

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There was a negative effect of baseline weight over the 12 month interval (estimate = 0.81, p = 0.0066) but a positive effect of treatment over that period (estimate = 1.21, p = 0.03)

These treatments interact with the GLP-1 receptor, supporting improved insulin secretion, regulating blood sugar levels, and reducing appetite