Participants were assigned to either melatonin ( n = 86, 2 mg daily for 8 weeks) or control ( n = 75) groups
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In addition, the GPx defends against oxidants that cause neuronal and protein damage, which reduce H 2 O 2 and lipid peroxide to water and alcohol, respectively
It can be caused by an injury, bump, or natural variations in shoulder bone structure
In addition to the role of iron metabolism in ferroptosis, an increasing number of other metabolic pathways have been implicated in ferroptosis, including the cyst(e)ine/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis, the guanosine triphosphate cyclohydrolase 1 (GCH1)/tetrahydrobiopterin (BH 4 )/dihydrofolate reductase (DHFR) axis, and the ferroptosis suppressor protein 1 (FSP1)/ coenzyme Q (CoQ) axis [8]
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