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*adapted from American Diabetes Association 2024 Standards of Care in Diabetes Available GLP-1 Receptor Agonists (GLP-1 RA) The Table below compares currently available GLP-1RA formulations, notes on their dosing and administration schedule, adjustments and demonstrated cardiorenal benefits

Albiglutide and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Cardiovascular Disease (Harmony Outcomes): A Double-Blind, Randomised Placebo-Controlled Trial

Muscle Mass and Glucagon-Like Peptide-1 Receptor Agonists: Adaptive or Maladaptive Response to Weight Loss? Circulation

This results in an increase of carnitine inside the muscle cell

Isotretinoin possibly reduces disease progression