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Preclinical studies indicate that BSA@LIR-PMF effectively targets inflamed vascular sites and demonstrates substantial therapeutic efficacy, supporting its potential as a clinically translatable nanomedicine platform for cardiovascular intervention in diabetic patients [161] ( Fig

Analysis of the national multicenter study (1976 to 1985) Smilkstein MJ, Knapp GL, Kulig KW, Rumack BH

Novo Nordisk), semaglutide (Ozempic, Rybelsus

Semaglutide stimulates glucose-dependent insulin secretion, meaning it triggers insulin release when blood glucose is elevated but does not cause problematic hypoglycemia in people without diabetes because it stops working when glucose normalizes

DOI: 10.1080/13696998.2026.2646078

So instead of choosing between one or the other, you are using a more layered approach