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Some research has explored GH and GLP-1 interactions in the context of metabolic syndrome, but these studies do not address the triple-agonist profile of retatrutide

This triggers overexpression of lipogenic enzymes, increasing intrahepatic fat production and promoting hepatic inflammation (66, 67)

Consequently, further investigations are necessary to clarify these results

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At the same time, an increase in inflammatory cytokine levels, such as IL-10, was observed in a concentration-dependent manner