The phase III trials of liraglutide, semaglutide, and tirzepatide all showed improvements in self-reported physical functioning [14, 43, 44]
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In the event of a GS mutation, a multitude of additional amino acid biosynthetic pathways are known to undergo compensatory activation, encompassing arginine-proline, glycine-serine-threonine, and alanine-aspartate-glutamate metabolism
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18 Longer-acting GLP-1 RAs are associated with less robust effects on postprandial glucose and greater effects on fasting glucose
10.1038/s41568-022-00459-0 81 LeiJ.LuoD.XiongJ.LiM