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therefore, data on its pathophysiological mechanisms are scarce

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Abstract Risk factors for most autoimmune diseases are multifactorial genetic variants modified by environmental risk factors

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These studies underscore that the effects of serine might depend on the type of infiltrating immune cells (Tregs or Teffs) and their specific isomer, being an interesting target for supplementation in tumors with a high ratio of infiltrated Teffs/Tregs