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Postgrad Med 2020;132(sup2):3-14.Article 23

Cerebral glucose metabolism and cerebral blood flow in thyroid dysfunction: an activation likelihood estimation meta-analysis

A bursa is a fluid filled sac that decreases friction between two tissues

These include alterations in the monoaminergic system, changes in glutamatergic synaptic transmission, neuro-inflammation, alterations in the hypothalamic-pituitary-adrenocortical (HPA) axis, changes in brain-derived neurotrophic factor (BDNF), and hippocampal atrophy ( However, depression in AD is more specifically linked to deficits in certain brain regions and AD-related pathological changes

But on April 7, when the study came out, much of the media unfortunately went overboard

Specific event rates included nausea (55% vs 12.6%), constipation (30.7% vs 11.6%), and vomiting (26.1% vs 4.1%)