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This enzymatic action depletes the available intracellular pool of nicotinamide, directly limiting the synthesis of nicotinamide adenine dinucleotide (NAD+)

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Advertisement - Continue Reading Below Tick bite CDC / James Gathany What it looks like : The most recognizable reaction on this list is the bullseye rasha large, red, target-like rash that signals the early stages of Lyme disease from the bite of an infected blacklegged tick