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Patients should be advised to: Aim for 6-8 glasses of fluid daily (approximately 1.52 litres), as recommended by the NHS, unless on a fluid restriction Note: patients with heart failure, chronic kidney disease, or other conditions requiring fluid restriction should follow their clinician's specific guidance Increase fluid consumption during episodes of nausea, vomiting, or diarrhoea Monitor urine colour as a simple indicator of hydration status (pale yellow suggests adequate hydration) Ensuring adequate electrolyte intake through dietary sources is essential

Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomics

Reduced nicotinamide mononucleotide is a new and potent NAD + precursor in mammalian cells and mice

Concluding remarks Behavioral feeding responses are evolutionarily conserved and necessary for survival

A study in a Chinese POI pedigree identified BNC1 mutations that lead to premature follicular activation and atresia (Zhang et al., 2018)

256 Roeikjer, J