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These strategies aim to improve the tolerability of the drug by allowing for a gradual increase in dosage

These therapies, primarily administered as subcutaneous injectables for ease of at-home use, act by mimicking the native GLP1 hormone, enhancing glucose-dependent insulin secretion, suppressing glucagon release, lowering HbA1c levels, and promoting weight loss - all while carrying a minimal risk of hypoglycemia when used alone

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Peripherally, liraglutide delays gastric emptying, thus increasing the production of other peripheral satiety signals (235)

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Protective effect of sucrose and antioxidants on cryopreservation of sperm motility and DNA integrity in C57BL/6 mice