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12 Free radicals are generated when NAPQI oxidizes thiol groups in proteins

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10.1111/jdi.12376 107 WangY.WuH.DongN.SuX.DuanM.WeiY.et al (2021)

Therefore, drugs that are able to down-regulate the activity of GSK-3 hold high promise of therapeutic effects for aging-related diseases

8 However, whether oxidative stress has a causal role in the development of hypertension and whether it may contribute to elevated blood pressure itself and/or vascular remodeling remains a matter of controversy

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