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The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies

Common side effects include: Nausea Diarrhea Vomiting Constipation Stomach pain These side effects are typically mild and decrease over time

Reduced inflammation Obesity is strongly linked to inflammation, and chronic inflammation is linked to longer menstrual cycles and follicular phases

Doses typically start at 0.25 mg and increase by 0.25 mg every 4 weeks until reaching a maintenance dose of 1.0 mg or 2.0 mg weekly

The investigational once-daily oral pill also reduced weight by an average of 16.0 lbs (7.9%) at the highest dose in a key secondary endpoint

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