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This creates a crosstalk that allows TM/SC cells to respond to changes in the ECM presumably induced by the mechanical forces on the TM/SC, aging and disease
Male rats receiving 1.2 mg/kg sertraline cumulatively until postnatal day 126 exhibited significantly reduced male potency (based on various indices of mating and fertility), while cumulative treatment significantly increased the number of fetal congenital malformations and reduced the numbers of implantation sites and surviving fetuses
The FDX1-mediated process culminates in profound proteotoxic stress driven by the aggregation of lipoylated mitochondrial proteins and the concomitant destabilization of Fe-S cluster proteins, which together lead to acute mitochondrial failure [3]
Diuretics and forced diuresis should be avoided
Collagen and proteoglycan abnormalities in the GDF-5-deficient mice and molecular changes when treating disk cells with recombinant growth factor
279 (6), L1005L1028
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