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Examples are the thylakoid lumen, the interior of the endoplasmic reticulum, and the vacuole

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Further, human islet architecture has a more favourable organisation for paracrine signalling when compared with mouse islets [22, 31]

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The diagnosis is supported by characteristic findings, including macrocytic anemia, low serum vitamin B12 levels, and abnormal results on gastroscopy or spinal MRI [5]