[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Holst J.J
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They discovered that exposure to GLP-1 receptor agonists was linked with heightened pre-term birth risk when prescribed for diabetes treatment, but not amongst those using the medication for weight management
Clinical recommendations based upon the patient's renal function include [see Dosage and Administration (2.2), Clinical Pharmacology (12.3)]: Drug Interactions The concomitant use of JANUMET XR with specific drugs may increase the risk of metformin-associated lactic acidosis: those that impair renal function, result in significant hemodynamic change, interfere with acid-base balance or increase metformin accumulation [see Drug Interactions (7)]
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