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Thyroid C-cell warning: Rodent C-cell tumor findings underlie the labeled MTC/MEN-2 caution for approved GLP-1 drugs (human relevance uncertain), and it carries over to the semaglutide arm

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, in efflux from cancer cells as the cause for their chemo-resistance) and in the mechanisms responsible for the dose-limiting kidney toxicity of cisplatin and for its years-long terminal half life [63,64,65]

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