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These IFN signatures may reflect exposure to viral infections, with Coxsackieviruses B proposed as possible environmental triggers of islet autoimmunity 9,10 or to other danger signals

doi: 10.1016/S0140-6736(16)31678-6 44 DixitT

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Urinary metabolomics of young Italian autistic children supports abnormal tryptophan and purine metabolism

References: [1] Pfeffer MA, et al