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Similarly, withaferin-A is very effective in downregulating the expression levels of MMP-2 and MMP-9

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therefore, three strains of Lactobacillus , each shown alone to have a protective effect against the development of EAE when administered before disease onset, were shown to inhibit established disease when administered as a therapeutic mixture

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Any long-term claim about KLOWs safety profile is outside the current preclinical evidence base