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High prevalence of diagnosed and undiagnosed polyneuropathy in subjects with and without diabetes participating in a nationwide educational initiative (PROTECT study)
doi: 10.1016/j.eclinm.2025.103363
In the STEP 1 trial, nausea, diarrhoea, vomiting or constipation affected around 74% of people on semaglutide, compared with about 48% on placebo, and a small number stopped treatment because of side effects
Substantial weight losstypically 5-10% or more of baseline body weightproduces measurable improvements in cardiovascular risk factors , including blood pressure, lipid profiles, inflammatory markers, and glycemic control
However, semaglutide may slow how quickly your body absorbs oral pills
And the list of drugs capable of causing depression is far longer than most people realize
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