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Therefore, it is very significant to suppress the activity of GSTP in disease cells

Since fundamental biochemical pathways evolved in the absence of molecular oxygen, most intracellular disulfides are rather transient and most cysteinyl residues are kept in a reduced state with the help of the thioredoxin or the glutathione/glutaredoxin system 7,63,77

Ma, J., Wu, Y., Ma, L., Yang, X., Zhang, T., Song, G., Li, T., Gao, K., Shen, X., Lin, J., Chen, Y., Liu, X., Fu, Y., Gu, X., Chen, Z., Jiang, S., Rao, D., Pan, J., Zhang, S., & Gao, Q

Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells

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