8 , e3221 (2014)
Moreover, garlic mitigates anxiety and depressive behaviors in diabetic rats, potentially through the reduction of oxidative stress in the brain (163)
This Glutathione S-transferase affinity transfection-positive cell sorting method is simple and fast to operate, large-instrument free, low cost, and hence possesses great potential in gene function study in vitro
It was observed that the overexpression of PINK1 in a Drosophila model of HD resulted in the amelioration of Parkin-mediated mitophagy defects and the attenuation of mHtt-induced neurotoxicity
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However, under defined pathophysiological stresses, including inflammatory cues, metal overload, cysteine deprivation, or drug exposure, GSH oxidation and thiol chemistry may become coupled to metal redox cycling and mitochondrial damage amplification, thereby increasing susceptibility to forms of regulated cell death such as ferroptosis and cuproptosis