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Furthermore, the combination with chemotherapy increases normal-tissue toxicity and therefore leads to even further reduction of the tolerable maximum dose [7]

This is due to the diverse composition of substances in a herbal drug that can have synergistic or additive effects [38]

Amitriptyline plus hydrodistension versus hydrodistension alone for treating interstitial cystitis/ bladder pain syndrome

The area surrounding the hair follicle is made of collagen and elastin

A negative feedback transcription cycle is eventually formed to maintain the oscillation of the gene expression (Kiyohara et al., 2006

elastin, proteoglycans, and glycosaminoglycans production