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However, affordability emerged as the primary driver of treatment discontinuation, with economic barriers disproportionately limiting long-term access and continuity of care

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10.1016/j.tifs.2020.01.026 [DOI] [Google Scholar] Zhang, X

Front Pharmacol 15:1405423

Combining both remains well-tolerated when each is dosed conservatively and escalated gradually

Also, in the Researching Cardiovascular Events With a Weekly Incretin in Diabetes (REWIND) study, approximately 10 thousand patients with type 2 diabetes and history of CVD or cardiovascular risk factors were randomized to a weekly subcutaneous injection of dulaglutide 1.5 mg or placebo [16]