For instance, the butyrate-producing Butyribacter showed positive correlations with neuroactive metabolites L-Asparagine, while these metabolites exhibited inverse correlations with expression of neuroinflammatory genes Tbx and Arhgdib, demonstrating how tooth loss-induced depletion of Butyribacter led to reduced levels of neuroprotective metabolites (particularly L-Asparagine), which subsequently resulted in upregulation of neuroinflammatory markers (Tbx1 and Arhgdib), thereby establishing a mechanistic pathway from tooth loss to neuroinflammation through the oral-gut-brain axis (Ji et al., 2025)
10.1016/0197-2456(95)00134-4 89 JansenF.YangX.FranklinB
It may also decrease blood pressure, cholesterol, wrinkles, and cellulite
57 longitudinal study Of Gh secretion, somatomedin and growth in the two years following cranial irradiation
A.GarciaS.DuchampC.et al (2014)
Exercise also reduces stress and improves sleep, both of which regulate hunger hormones and support sustained weight loss