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Strengths and weaknesses of this review This systematic review and meta-analysis was registered and reported with PRISMA [21] and included the full of original trials whenever possible

In HepG2 cells morphological changes could be observed after 24 h at 25 M, while the IC 25 (MTT assay

The relationship runs both ways

Although the committee's recommendations often carry significant weight in the FDA's decision-making, they are advisory rather than binding

Marchi S, Patergnani S, Pinton P (2014) The endoplasmic reticulummitochondria connection: one touch, multiple functions

The regulation of iron balance is mostly achieved by the synthesis and release of iron homeostasis regulators by hepatocytes, such as transferrin receptor (TFR), ferritin, and ferroportin (FPN) [68-70]