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Supplementation is unnecessary if parenteral therapy repletes serum levels, but individual assessment is advised
Additionally, there are certain classes of medications that hinder healing, including immunosuppressants, corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs), and anticoagulants
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Nebivolol, a third-generation beta-blocker, was shown to stimulate eNOS activity in ex vivo tests, leading to the induction of vascular nitric oxide, which explains why individuals with essential hypertension had better NO bioavailability (197, 198)
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