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doi: 10.1002/rth2.12283 19 EstvezF.De AngeloT.VesellE

With this protein source, it seems that one key player in the oligopeptide stimulation of GLP-1 release is peptide transporter 1 (PepT1) (Fig

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The molecule contains a cysteine-linked disulfide bridge that constrains the peptide into a cyclic conformation, an important feature for maintaining its signaling profile in biochemical and adipocyte-based assays

The consequences of Nrf2 impairment in CF include weakened intrinsic antioxidant defense capacity and increased intracellular H 2 O 2 levels, which contribute to the overproduction of pro-inflammatory cytokines like IL-6 and IL-8, directly linking defective antioxidant response to CFs characteristic chronic inflammation (Chen et al., 2008)

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